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Tissue Pressure Research Projects
Measurement of Intramuscular Pressure in Compartment Syndrome Purpose: Compartment syndrome is a condition in which high pressure within a closed fascial compartment reduces blood perfusion below the level necessary for tissue viability causing tissue damage and intense pain. Acute Compartment Syndrome (ACS) can be caused by tibial fracture, trauma resulting in edema, hemorrhage, venous constriction, or burns. Chronic exertional compartment syndrome (CECS) develops over time with repeated strenuous exercise resulting in abnormally increased intramuscular pressure (IMP) at rest, during exercise, and following exercise. Increasing leg pain associated with CECS typically causes the subject to cease activity in order to attain relief.  Although it is largely a self-limiting condition found in adult recreational and elite runners, athletes, and military recruits, it can lead to more severe conditions including ACS and acute kidney injury with the risk of death. The preferred clinical method for decompressing these painful compartments is by fasciotomy. The goal of this project is to nonivasively measure pressure, blood flow, and amount of oxygen before, during, and after exercising in healthy subjects and patients being evaluated for CECS. Hypothesis: We hypothesize that there will be a difference in perfusion and oxygenation values between control and experimental conditions. Technologies Used: Single leg chamber, PPG, NIRS, and The CareGuide
RESEARCH Space Physiology Sports Medicine Microvascular Flow
Tissue Pressure